Endoglin anticorps (FITC)

N° du produit ABIN319843

Cet anticorps Souris Monoclonal détecte spécifiquement Endoglin dans FACS. Il présente une réactivité envers Humain et Cheval.

Aperçu rapide pour Endoglin anticorps (FITC) (ABIN319843)

Antigène: Endoglin (ENG)

Reactivité: Humain, Cheval

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Endoglin est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Clone: SN6

Détail du produit anti-Endoglin anticorps (FITC)

Specificité: SM1177F recognizes the CD105 cell surface antigen.

Purification: Affinity Chromatography on Protein G.

Immunogène: Partially purified cell membrane antigens from fresh leukaemia cells. Spleen cells from immunised BALB/c mice were fused with cells of the mouse P3/NS1/1-Ag4-1 myeloma cell line

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry (use 10 μL of neat antibody to label 10^6 cells in 100 μL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as a preservative and 1 % BSA as a stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Endoglin

Antigène: Endoglin (ENG)

Autre désignation: CD105 / Endoglin

Sujet: CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2. CD105 is a glycoprotein homodimer of 95 kD subunits. CD105 is expressed by endothelial cells, activated monocytes and some leukaemia cells.Synonyms: END, ENG, HHT1, ORW, ORW1

ID gène: 9606

UniProt: P17813